The evolution of 1st to Indigestion 3rd generation electrochemical biosensors reflects a simplification and enhancement of the transduction pathway.However, in recent years, modification of the transducer with nanomaterials has become increasingly studied and imparts many advantages.The sensitivity and overall performance of enzymatic biosensors ha
HIV protease cleaves the antiviral m6A reader protein YTHDF3 in the viral particle.
N6-methyladenosine (m6A) is the most abundant HIV RNA modification but the interplay between the m6A reader protein YTHDF3 and HIV replication is not well understood.We found that knockout of YTHDF3 in human CD4+ T-cells increases infection supporting the role of YTHDF3 as a restriction factor.Overexpression of the YTHDF3 protein in the producer ce
Trustworthy Blockchain Oracles: Review, Comparison, and Open Research Challenges
The Water Filtration Cartridges essence of blockchain smart contracts lies in the execution of business logic code in a decentralized architecture in which the execution outcomes are trusted and agreed upon by all the executing nodes.Despite the decentralized and trustless architectures of the blockchain systems, smart contracts on their own cannot